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Abstract #2953

Liver MR imaging using 3D phase-sensitive inversion recovery (PSIR) sequence

Yasuhiro Fujiwara1, Hirotoshi Maruyama2, Nobuyuki Kosaka3, Yoshiyuki Ishimori4, and Noriyuki Furukawa2

1Department of Medical Imaging, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan, 2Radiological Center, National Hospital Organization Kumamoto Medical Center, Kumamoto, Japan, 3Department of Radiology, University of Fukui, Fukui, Japan, 4Department of Radiological Sciences, Ibaraki Prefectural University of Health Sciences, Ibaraki, Japan

We applied 3D phase-sensitive inversion recovery (PSIR) sequence to liver MR imaging. Experiments with phantom and healthy subjects revealed that this sequence improved contrast enhancements of Gd-based agents and liver-to-spleen or muscle contrasts while simultaneously providing an accurate T1 map of the liver. Better Gd contrast enhancements and liver contrasts may improve tumor-to-liver contrasts in the hepato-biliary phase with Gd-based hepatocyte-specific contrast agents, and the accurate T1 map may be useful for liver-function assessments. Although a clinical study is required to evaluate its utility, this sequence may have potential to improve liver MR imaging.

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