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Abstract #2975

Rectal Cancer: Apparent Diffusion Coefficient Value and Clinical-Pathologic Factors Associated with Local Recurrence or Distant Metastases

Yoshifumi Noda1, Satoshi Goshima1, Hideto Tomimatsu1, Haruo Watanabe1, Hiroshi Kawada1, Nobuyuki Kawai1, Hiromi Ono1, Masayuki Matsuo1, and Kyongtae T Bae2

1Radiology, Gifu University Hospital, Gifu, Japan, 2Radiology, University of Pittsburgh Medical Center, Pittsburgh, PA, United States

To determine the ADC value and clinical-pathologic risk factors associated with postoperative local recurrence or distant metastases in patients with rectal cancer. The plasmatic CA19-9 level (P = 0.0027), pathological N stage (P = 0.0018), lymphatic invasion (P < 0.0001), and ADC value (P = 0.0076) were independently associated with postoperative local recurrence or distant metastases in the patients with rectal cancer. Among the several indicators, the tumor ADC values and plasmatic CA19-9 level can be useful for the preoperative prediction of high risk cases for postoperative local recurrence or distant metastases in patients with rectal cancer.

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