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Abstract #3100

Assessment of brain structural abnormalities and the correlation with inhibitory control in betel nut chewers with DTI

Te-Wei Kao1, Ming-Chou Ho2, and Jun-Cheng Weng1,3

1Department of Medical Imaging and Radiological Sciences, Chung Shan Medical University, Taichung, Taiwan, 2Department of Psychology, Chung Shan Medical University, Taichung, Taiwan, 3Department of Medical Imaging, Chung Shan Medical University Hospital, Taichung, Taiwan

Betel nut is one of the common addictive substances in many countries. The brain influence of cocaine, alcohol, and tobacco cigarette have been studied by several studies. However, only few studies focused on the brain influence of betel nut, and most of them used fMRI or PET. Thus, our study aim was to use diffusion tensor imaging (DTI) to evaluate the impact of neurological structure of white matter caused by betel nut. The brain structural differences between the betel nut chewers and healthy controls and the correlation with inhibitory control were also discussed. Our results pointed out the significant neurological structural differences in the insula, amygdala and putamen of DTI indices between the betel nut chewers and healthy controls.

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