Chiao-Ning Chen1, Hsiao-Hui Huang1, Ming-Ting Wu2, and Teng-Yi Huang1
1Electrical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan, 2Radiology, Kao-Hsiung Veterans General Hospital, Kao-Hsiung, Taiwan
This study attempted to improve the accuracy of T1
fitting and image registration for automatic extracellular volume
fraction mapping. We proposed to use multiple initial values in the T1 fitting
procedure and the results prominently exhibited less errors. For the image registration, we first
performed the automatic segmentation of left-ventricle (LV) walls based on an
image synthesis approach and then used the obtained LV masks for the deformable
image registration. The results supported that the method significantly
improved the overlap rate between the pre- and postcontrast images as well as
the accuracies of the obtained ECV maps.
