Abstract #3289

How to minimize motion-induced phase and magnitude modulation in diffusion-prepared sequences?

Anh Tu Van¹, Barbara Cervantes², Ernst J Rummeny², Axel Haase¹, and Dimitrios Karampinos²

¹Zentralinstitut für Medizintechnik, Technische Universität München, Garching, Germany, ²Diagnostic and Interventional Radiology, Technische Universität München, Munich, Germany

Diffusion-preparation is regaining popularity recently thanks to its compatibility with any type of readout scheme. Using Bloch simulations, the current work provides understanding of the motion-induced magnitude and phase modulation of the signal obtained with diffusion-prepared sequences. When motion induces a constant phase across the voxel, dephasing signal before tipping up and rephasing it before readout should be used to remove motion-induced magnitude modulation. When the induced phase is not constant, smaller voxel sizes assist towards stabilizing both magnitude and phase of the signal. In vivo data using diffusion-prepared 3D TSE are shown supporting the observations of the Bloch simulations.

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