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Abstract #3317

Imaging of thalamic substructures: T1 based approach using IR-EPI sequence at 7T

Se-Hong Oh1, Ken Sakaie1, Stephen E. Jones1, and Mark J. Lowe1

1Imaging Institute, Cleveland Clinic Foundation, Cleveland, OH, United States

Accurate identification of the thalamus sub-structures is therefore important for localization of specific nuclei and for the understanding of brain function. However, sub-structures of the thalamus are so small and have intermediate signal characteristics between grey/white matter it has been difficult to identify them with conventional MR imaging technique. In this work, in-vivo T1 value at 7T are measured using fast T1 mapping technique in less than 2 min and optimized inversion time to generate optimal contrast from the thalamus. The optimized results reveal markedly improved anatomical detail of the sub-structures of the thalamus, including their detailed locations.

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