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Abstract #3334

Highly-Accelerated, Self-Calibrated Stack-of-Spirals Arterial Spin Labeling Using 3D SPIRiT Reconstruction

Yulin V Chang1, Marta Vidorreta2, Ze Wang3, and John A Detre2

1Radiology, University of Pennsylvania, Philadelphia, PA, United States, 2Neurology, University of Pennsylvania, Philadelphia, PA, United States, 3Hangzhou Normal University, Hangzhou, Zhejiang, China, People's Republic of

3D coverage of the whole brain by using RARE-refocused stack-of-2D-spirals often suffers from low temporal/spatial resolution due to the long spiral readout or long echo train. In this work we present a method that allows whole-brain coverage at 3 mm isotropic spatial resolution with one- or two-segment, accelerated acquisitions in both partition and spiral directions. The technique was applied in conjunction with background-suppressed pCASL, resulting in improved temporal/spatial resolution for quantification of cerebral blood flow.

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