Super-Resolution MR imaging of ex-vivo eye-globe structures at 7T
Se-Hong Oh1, Stephen E. Jones1, Arun Singh2, and Mark J. Lowe1
1Imaging Institute, Cleveland Clinic Foundation, Cleveland, OH, United States, 2Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, OH, United States
We demonstrate a high-resolution ex-vivo globe
image using 7T. With voxel size of 250μm isotropic resolution, detailed
structures of the globe were clearly identified.
results show that the high-resolution MR imaging is particularly useful in
helping to visualize inner structure of eye-globe. Moreover, it is successfully
demonstrated the sensitivity to choroidal melanoma. In addition, we have performed
MRI scans using human globe specimens to investigate the contribution of
fixation to the evolution of T2 over time and measured SNR changes
as function of the number of excitations to gain some insight into the optimal
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