Dandan Huang1, Hongyan Ni2, Dan Liu2, and Tianyi Qian3
1First Central Clinical College, Tianjin Medical University, Tianjin, China, People's Republic of, 2Tianjin, China, People's Republic of, 3Beijing, China, People's Republic of
previous studies have tried to use MRS to investigate changes in brain
function. In this study, we used a MEGA-PRESS sequence to measure the GABA and
Glx concentration of normal controls, normal elderly controls, and patients
with mild cognitive impairment and Alzheimer's disease. In ACC, the Glx showed
significant differences between each groups, and the GABA showed significant
aging effects in normal subjects.