A combined microcoil and microdialysis approach to measure metabolic response in real-time.
Stefan Glöggler1, Silvia Rizzitelli2, Noel Pinaud3, Gérard Raffard2, Véronique Bouchaud2, Stéphane Sanchez2, Alan Wong4, and Yannick Crémillieux2
1University of Southampton, Southampton, United Kingdom, 2CRMSB, Université Bordeaux, Bordeaux, France, 3Université Bordeaux, Bordeaux, France, 4CEA Saclay, Gif-sur-Yvette, France
We present two highly sensitive microcoil probes (1H and 13C) that are connected to microdialysis probes inside a MRI scanner. Under continuous flow conditions the metabolic response can be monitored in real-time in vitro and in vivo.
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