Effect of exposure in hypoxia environment caused by high altitude on magnetic susceptibility in human brain assessed by quantitative susceptibility mapping
Dandan Zheng1, Wenjia Liu2, Bing Wu1, and Lin Ma2
1MR Research China, GE Healthcare, Beijing, China, People's Republic of, 2Radiology Department, Beijing Military General Hospital, Beijing, China, People's Republic of
Cerebrospinal
fluid fraction, CBF and T2 decay have been reported to be related with hypoxia
caused by high altitude in previous studies. All these biomarkers maybe
associate with tissue homogeneous magnetism changes, which may result in the
magnetic susceptibility changes. Quantitative susceptibility mapping (QSM) is a
novel technique that allows mapping of tissue magnetic susceptibility. It has
the potential to be more sensitive with respect to magnetic tissue properties than
conventional magnitude-based
techniques such as transverse relaxation rates. This study was designed to
reveal the effect of exposure in hypoxia environment on magnetic susceptibility
in human brain assessed by QSM.
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