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Abstract #3711

MRI Assessment of Acute Pathologic Process after Myocardial Infarction: Role of Magnetic Nanoparticle-based MRI

Cheongsoo Park1,2, Eun-Hye Park3, Jongeun Kang1,4, Kiyuk Chang3, and Kwan Soo Hong1,4,5

1Korea Basic Science Institute, Cheongju, Korea, Republic of, 2The Catholic University of Korea, Seoul, Korea, Republic of, 3Seoul St. Mary’s Hospital and College of Medicine, Seoul, Korea, Republic of, 4Chungnam National University, Daejeon, Korea, Republic of, 5University of Science and Technology, Daejeon, Korea, Republic of

Myocardial infarction (MI) is the major cause of sudden death in most industrialized society. Imaging of early disease progression and investigation of relationship between myocardial necrosis and successive inflammatory response are needed for optimal treatment of MI. We conducted cardiac MR imaging of disease progression in acute MI by using three different MRI methods of Gd (LGE), Mn (ME), and iron oxide nanoparticles (MNP)-based MRI for estimation of infarcted and inflammatory regions.

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