Mu-Lan Jen1, Islam S. Hassan2, Ping Hou1, Guang Li1, Ashok J. Kumar2, Colen R. Rivka2, and Ho-Ling Liu1
1Department of Imaging Physics, The University of Texas M. D. Anderson Cancer Center, Houston, TX, United States, 2Department of Diagnostic Radiology, The University of Texas M. D. Anderson Cancer Center, Houston, TX, United States
This study evaluates
the errors associated with the spatial transformation process by using
algorithms commonly applied for clinical pre-surgical fMRI. The images from nine
right-handed patients with brain tumors were retrospectively
analyzed. Significant differences (P<0.05) were
found when comparing results from automated registration (AR) vs. coordinate
matching (CM) and
AR vs. AR with manual
adjustment (AR, adjusted). No statistical significance
was found between CM and AR, adjusted. This study established a platform for evaluating
the functional localization accuracy in pre-surgical fMRI, and highlighted the
necessity of quality control for the AR processing as a clinical routine.
