Meeting Banner
Abstract #3819

Sample entropy (SampEn) differentiate patients with Major Depressive Disorder (MDD) from healthy controls and explores mechanism of MDD

Kai Wang1, Yunwen Shao1, Tongxin Chen1, Chuangjian Cai1, Yan Zhu2, and Kui Ying3,4

1Department of Biomedical Engineering, Tsinghua University, Beijing, China, People's Republic of, 2Psychiatry Department, Yu Quan Hospital, Tsinghua University, Beijing, China, People's Republic of, 3Department of Engineering Physics, Tsinghua University, Beijing, China, People's Republic of, 4Key Laboratory of Particle and Radiation Imaging, Ministry of Education, Beijing, China, People's Republic of

Entropy indicates system irregularity. Sample Entropy (SampEn), an estimation of entropy in a relatively robust way, was used to differentiate patients with Major Depressive Disorder (MDD) from healthy controls and to explore the mechanism of MDD. In this work, we found five clusters with significantly different SampEn in MDD group from that of control group, located in left frontal lobe, left parietal lobe, left temporal lobe, cerebellum and occipital lobe respectively, and the overall accuracy obtained with linear support vector machine formed by SampEn of those regions was 86.7%(p=0.000).

This abstract and the presentation materials are available to members only; a login is required.

Join Here