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Abstract #3848

Liver parenchymal T1: repeatability and studies in a rodent model of chronic liver disease at 9.4T

Manil Chouhan1, Rajiv Ramasawmy2, Adrienne Campbell-Washburn2, Alan Bainbridge3, Nathan Davies4, Shonit Punwani1, Rajeshwar Mookerjee4, Simon Walker-Samuel2, Mark Lythgoe2, and Stuart Taylor1

1UCL Centre for Medical Imaging, University College London, London, United Kingdom, 2UCL Centre for Advanced Biomedical Imaging, University College London, London, United Kingdom, 3Department of Medical Physics, University College London Hospitals NHS Trust, London, United Kingdom, 4UCL Institute for Liver and Digestive Health, University College London, London, United Kingdom

There is a growing interest in the use of hepatic parenchymal T1 for the assessment of hepatic fibrosis. Using Look-Locker T1 measurements at 9.4T in a rat model of cirrhosis, we demonstrate that these measurements are repeatable and significantly different in animals with and without chronic liver disease.

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