Abstract #3874

MR based body composition analysis correlates ayurvedic phenotyping

Rama Jayasundar¹, Somenath Ghatak¹, Ariachery Ammini², Ashok Mukhopadhyaya³, and Arundhati Sharma⁴

¹NMR, All India Institute of Medical Sciences, New Delhi, India, ²Endocrinology, All India Institute of Medical Sciences, New Delhi, India, ³Laboratory Medicine, All India Institute of Medical Sciences, New Delhi, India, ⁴Anatomy, All India Institute of Medical Sciences, New Delhi, India

The world is entering an era of personalised medicine and phenotyping individuals is gaining much attention. In this context, genetic basis of the comprehensive phenotyping in ayurveda, the indigenous medicine of Indian subcontinent has drawn much scientific interest. This study reports an innovative application of MR in providing the much needed objective parameters for some of the phenotyping indices. Interestingly, the results show that the phenotypes mentioned in ayurveda as being predisposed to diabetes are found to not only have increased localised fat deposition (abdomen and thigh) (measured by MRI) and triglyceride levels but also lower insulin sensitivity.

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