Abstract #3919

The effect of flip-angle on body composition using calibrated water-fat MRI.

Thobias Romu^1,2, Janne West^2,3, Anna-Clara Spetz Holm⁴, Hanna Lindblom³, Lotta Lindh-Åstrand⁴, Mats Hammar⁴, Magnus Borga^1,2, and Olof Dahlqvist Leinhard^2,3

¹Department of Biomedical Engineering, Linköping University, Linköping, Sweden, ²Center for Medical Image Science and Visualization (CMIV), Linköping University, Linköping, Sweden, ³Department of Medical and Health Sciences (IMH), Linköping University, Linköping, Sweden, ⁴Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden

This study tested how the flip angle affects body composition analysis by MRI, if adipose tissue is used as an internal intensity reference. Whole-body water-fat images with flip angle 5° and 10° were collected from 29 women in an ongoing study. The images were calibrated based on the adipose tissue signal and whole-body total adipose, lean and soft tissue volumes were measured. A mean difference of 0.29 L, or 0.90 % of the average volume, and a coefficient of variation of 0.40 % was observed for adipose tissue.

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