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Abstract #3933

MR spectroscopy in the differentiation of benign, borderline and malignant cystic epithelial ovarian tumors

Feng-Hua Ma1, Guo-Fu Zhang1, Jin-Wei Qiang2, Ya-Min Rao3, Song-Qi Cai4, and Hai-Min Li4

1Department of Radiology, Obstetrics & Gynecology Hospital, Shanghai Medical College,Fudan University., Shanghai, China, People's Republic of, 2Department of Radiology, Jinshan Hospital, Shanghai Medical College,Fudan University, Shanghai, China, People's Republic of, 3Department of Radiology, Obstetrics& Gynecology Hospital, Shanghai Medical College, Fudan University, Shanghai, China, People's Republic of, 4Department of Radiology, Jinshan Hospital, Shanghai Medical College, Fudan University, Shanghai, China, People's Republic of

Because of the overlap in the imaging appearances of the benign, borderline, and malignant tumors, a considerable portion of cystic epithelial ovarian tumors(EOT) cannot be correctly diagnosedon conventional MR imaging. Recently, the rapid development of software and hardware has enabled the increasing application of proton magnetic resonance spectroscopy (1H-MRS) in ovarian tumors. However, 1H-MRS studies are still preliminary. To our knowledge, in vivo 1H-MRS differentiation of a single type of histopathological and morphological tumors has not yet been studied. We prospectively performed in vivo 1H-MRS of 86 patients with cystic EOT to understand the spectroscopic characteristics of different types of tumors and to investigate the ability of 1H-MRS in the differentiation of benign, borderline and malignant EOT. The results shows that 1H-MRS patterns of benign, borderline and malignant cystic EOT are different. The Cho/Cr ratio increases with the higher malignancy and a high Cho peak indicates a malignant tumor. A significantly elevated NAA peak indicates a borderline tumor.

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Abstract