2D MR Spectroscopic Imaging of the Pediatric Brain using Compressed Sensing
Rohini Vidya Shankar1, Houchun Harry Hu2, John C Chang3, and Vikram D Kodibagkar1
1Biomedical Engineering, Arizona State University, Tempe, AZ, United States, 2Radiology, Phoenix Children's Hospital, Phoenix, AZ, United States, 3Banner MD Anderson Cancer Center, Gilbert, AZ, United States
The spatial variations in brain metabolite concentrations can be mapped
using magnetic resonance spectroscopic imaging (MRSI). The long scan times in
MRSI do not permit its inclusion in pediatric imaging protocols. MRSI
accelerated by compressed sensing was used to image the pediatric brain for
various acceleration factors 2X-5X. The retrospectively undersampled
reconstructions showed high data fidelity for up to 80% undersampling when compared
with the fully sampled reference dataset. Studies are underway to prospectively
acquire and validate CS accelerated MRSI data in pediatric patients.
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