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Abstract #4018

Longitudinal relaxation time editing for acetylcarnitine detection with 1H-MRS

Lucas Lindeboom1,2, Yvonne M.H. Bruls1,2, Petronella A. van Ewijk1, Matthijs K.C. Hesselink2, Joachim E. Wildberger1, Patrick Schrauwen2, and Vera B. Schrauwen-Hinderling1,2

1Radiology, Maastricht University Medical Center, Maastricht, Netherlands, 2Human Biology and Human Movement Sciences, Maastricht University Medical Center, Maastricht, Netherlands

The use of a long TE enables detection of acetylcarnitine with 1H-MRS. However, in (very) obese subjects, suppression of overlapping lipid resonances becomes problematic, even with long TE. We here show short T1 metabolites, such as lipids, can additionally be suppressed with a new T1 editing approach.

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