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Abstract #4123

Magnetic Resonance imaging features of normal and abnormal fetal Ganglionic Eminence. A pictorial essay.

Giorgio Conte1,2, Claudia Cesaretti1, Giana Izzo1, Cecilia Parazzini1, and Andrea Righini1

1Radiology and Neuroradiology, Children's Hospital V. Buzzi, Milan, Italy, 2Radiology Institute, University of Milan, Milan, Italy

Ganglionic eminence (GE) is the main proliferative structure of the ventral telencephalon and contributes to GABA-ergic cortical interneuron population; GE imaging characterization in normal and abnormal conditions is poor. After searching a 3500 cases fetal MR database, we illustrate normal GE features, its abnormalities and its possible associations. GE malformations are divided: 1) bilateral symmetric cavitations as inverted C shape separating GE from parenchyma; 2) GE volume increase associated or not with the above mentioned cavitation. About half of cases are associated with micro-lissencephaly, the others with minor-moderate anomalies. As group apart are presented clastic GE lesions, featuring haemorrhagic changes.

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