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Abstract #4224

Effect of a Low-Rank Denoising Algorithm on Quantitative MRI-Based Measures of Liver Fat and Iron

Brian C Allen1, Felix Lugauer2, Dominik Nickel2, Lubna Bhatti1, Randa A Dafalla1, Brian M Dale3, Tracy A Jaffe1, and Mustafa R Bashir1,4

1Radiology, Duke University Medical Center, Durham, NC, United States, 2MR Application Predevelopment, Siemens Healthcare GmbH, Erlangen, Germany, 3MR R&D Collaborations, Siemens Healthcare, Cary, NC, United States, 4Center for Advanced Magnetic Resonance Development, Duke University Medical Center, Durham, NC, United States

Applying the described low-rank denoising algorithm to a liver fat/iron quantification technique reduces image noise in PDFF and R2* maps without adversely affecting mean values of the quantitative measures or reader assessment of edge sharpness.

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