Characterizing metabolic profiles in non-enhancing gliomas using 3D MRSI
Yan Li1, Tracy L Luks1, Jason C Crane1, Sarah J Nelson1, and Tracy R McKnight2
1Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, United States, 2Tobacco-Related Disease Research Program, University of California, Oakland, CA, United States
This study
evaluated the metabolite profiles that were acquired using short and long echo
time (TE) magnetic resonance spectroscopic imaging (MRSI) for forty patients
with non-enhancing gliomas, including 25 grade 2 and 15 grade 3 gliomas. Metabolite
differences were detected between the lesions and white matter, as well as
between grades. There were also differences in the T2 values between
metabolites within the lesions that could influence the Cho/NAA ratios between
short and long TE MRSI.
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