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Abstract #4371

Estimation of the Evolution of Cerebral Ischemia by MRI with T1 Relaxation Time in Rotating Frame and Apparent Diffusion Coefficient

Yuefa Tan1, Ruiying Chen1, Bin Chen1, Juan Xu1, Daokun Ren1, Yingjie Mei2, Queenie Chan3, Yuankui Wu1, and Yikai Xu1

1Department of Medical Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou, China, People's Republic of, 2Philips Healthcare, Guangzhou, China, People's Republic of, 3Philips Healthcare, HongKong, China, People's Republic of

This study was to evaluate the abilities of T1ρ and ADC to estimate the duration of ischemia in human, and focus on clinical application. We take a cross-sectional study to collect patients with brain ischemia in period of time(March 2014 to February 2015), and exploit the characteristics of ADC and T1ρ in brain ischemia in various stages of ischemia and uncover their relationships with ischemia stages. Our results indicate that T1ρ parametric results were elevated in the ischemic lesion, and increased over time of ischemia in a linear fashion.

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