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Abstract #4417

White Matter Structural Alternations in Children with HIV Infection and Exposure

Marcin Jankiewicz1, Paul A. Taylor1,2,3, Martha Holmes1, Mark F. Cotton4, Barbara Laughton4, Andre J.W. van der Kouwe5, and Ernesta M. Meintjes1

1MRC/UCT Medical Imaging Research Unit, Department of Human Biology, University of Cape Town, Cape Town, South Africa, 2Scientific and Statistical Computing Core, National Institutes of Health, Bethesda, MD, United States, 3African Institute for Mathematical Sciences, Muizenberg, South Africa, 4Children’s Infectious Diseases Clinical Research Unit, Department of Pediatrics and Child Health, Stellenbosch University, Cape Town, South Africa, 5Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States

In this work we examine WM alterations in HIV infected children at age 7 years and compare those who initiated ART before and after 12 weeks of age.

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