Associations between quantitative MRI biomarkers in the lumbar spine and pain in chronic low back pain patients with disc degeneration
Volkan Emre Arpinar1 and L Tugan Muftuler1,2
1Neurosurgery, Medical College of Wisconsin, Milwaukee, WI, United States, 2Center for Imaging Research, Medical College of Wisonsin, Milwaukee, WI, United States
Associations between quantitative MRI
biomarkers in the lumbar spine and pain in chronic low back pain
patients (CLBP) were studied. These biomarkers are currently being explored as
quantitative metrics of disc degeneration. Since most CLBP cases are associated
with pathologic disc degeneration processes, these biomarkers might provide
clues about the actual source of pain. For analysis, the discs from each subject were pooled from the least to the most
degenerated one using a semi-quantitative metric. Results showed that these biomarkers
might aid in identifying the source of pain in CLBP patients.
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