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Abstract #0038

Simultaneous Multi-Slice Imaging For Whole Heart Myocardial T1 Mapping In A Single Breath-Hold

Sebastian Weingärtner1,2,3, Steen Moeller2, Kâmil Uğurbil2, Chetan Shenoy4, and Mehmet Akçakaya1,2

1Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN, United States, 2Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States, 3Computer Assisted Clinical Medicine, Heidelberg University, Mannheim, Germany, 4Department of Cardiology, University of Minnesota, Minneapolis, MN, United States

Myocardial T1-mapping bears promise for evaluation of numerous cardiomyopathies, but requires multiple breath-hold scans with conventional techniques. In this study we explored the acceleration potential of multi-band imaging for myocardial SAPPHIRE T1-mapping with 3-slice coverage in a single breath-hold. Three linear methods for slice and in-plane unaliasing were evaluated. Phantom studies confirmed the accuracy of the proposed T1-mapping method, and in-vivo evaluation has shown reliable image quality with 3-fold acceleration at the cost of 1.3 to 1.7-fold increased in-vivo variability. Smaller loss in-vivo precision was achieved using regularized methods, for the trade-off against increased inter-slice leakage.

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