Abstract #0187

PAM50: Multimodal template of the brainstem and spinal cord compatible with the ICBM152 space

Benjamin De Leener¹, Vladimir Fonov², D. Louis Collins², Virginie Callot^3,4, Nikola Stikov^1,5, and Julien Cohen-Adad^1,6

¹NeuroPoly Lab, Institute of Biomedical Engineering, Polytechnique Montreal, Montreal, QC, Canada, ²Montreal Neurological Institute, McGill University, Montreal, QC, Canada, ³Aix-Marseille Univ, CNRS, CRMBM UMR 7339, Marseille, France, ⁴CEMEREM, Hopital de la Timone, Pôle d’imagerie médicale, AP-HM, Marseille, France, ⁵Montreal Heart Institute, Montreal, QC, Canada, ⁶Functional Neuroimaging Unit, CRIUGM, Université de Montréal, Montreal, QC, Canada

Template-based analysis of multi-parametric MRI data of the spinal cord sets the foundation for multi-center studies with minimum bias, thereby helping the discovery of new biomarkers of spinal-related diseases. In this study, we introduce a spinal cord MRI template, the PAM50, which is anatomically compatible with the ICBM152 brain template and uses the same coordinate system. The fusion of the PAM50 and ICBM152 templates facilitates group studies and multi-center studies of combined brain and spinal cord MRI and also allows the use of existing atlases of the brainstem compatible with the ICBM template.

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