Abstract #0201

CEST Signals of Lipids

Steffen Goerke¹, Moritz Zaiss^1,2, Dario Longo³, Francesca Garello⁴, Enza Di Gregorio⁴, Johannes Breitling¹, Mark E Ladd¹, and Peter Bachert¹

¹Division of Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany, ²Department of High-field Magnetic Resonance, Max-Planck-Institute for Biological Cybernetics, Tübingen, Germany, ³Institute of Biostructure and Bioimaging, Consiglio Nazionale delle Ricerche (CNR), Turin, Italy, ⁴Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy

In this study, lipids were identified to be an important contributor to the upfield chemical exchange saturation transfer (CEST) signals of brain tissue. This finding can explain the pronounced CEST image contrast between gray and white matter observed in healthy volunteers.

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