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Abstract #0295

4D Flow MRI during Exercise in Prematurely Born Adults and Children

Jacob Macdonald1, Arij Beshish2, Kristin Haraldsdottir2, Marlowe Eldridge2, Oliver Wieben1,3, and Christopher J Francois3

1Medical Physics, University of Wisconsin - Madison, Madison, WI, United States, 2Pediatrics, University of Wisconsin - Madison, Madison, WI, United States, 3Radiology, University of Wisconsin - Madison, Madison, WI, United States

Preterm birth can result in impaired development of lung airways and vasculature, but the long term implications are unclear. With this in mind, we performed 4D flow imaging in the aorta and pulmonary artery during exercise at 70% maximal power in both children and adults who had been born prematurely to identify any differences in flow characteristics relative to healthy controls. Although no statistically significant differences were identified between our groups, some preterm cohorts showed increased cardiac output and mean velocity. The significance of these trends should become apparent as we continue to recruit subjects and increase our statistical power.

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