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Abstract #0357

Measuring Blood Oxygenation and Hematocrit with a Combined T2 and T1 Approach: Initial Experience in Humans

Thomas Christen1, Jia Guo1, Wendy Wei Ni1, Michael Moseley1, and Greg Zaharchuk1

1Radiology, Stanford University, Palo Alto, CA, United States

In this study, we propose to obtain simultaneous measurements of blood oxygen saturation (SO2) and hematocrit (Hct) by combining two or more in vivo measurements of blood MR relaxation times. We tested our approach in 5 healthy human subjects using T2+T1 values and calibration curves obtained in vitro. The results found in the superior sagittal sinus vein (SO2=62±5% and Hct=46±1%) are in good agreement with literature values and suggest great potential of the approach once it is further validated.

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