Abstract #0423

k-t accelerated aortic 4D flow MRI in under 2 minutes: feasibility and impact of resolution, k-space sampling patterns, and respiratory navigator gating on hemodynamic measurements

Emilie Bollache¹, Alex J. Barker¹, Jeremy D. Collins¹, Pim van Ooij², Rouzbeh Ahmadian¹, Alex Powell¹, James C. Carr¹, Julia Geiger¹, and Michael Markl^1,3

¹Department of Radiology, Northwestern University, Chicago, IL, United States, ²Department of Radiology, Academic Medical Center, Amsterdam, Netherlands, ³Department of Biomedical Engineering, Northwestern University, Chicago, IL, United States

Our objective was to assess the performance of eight highly k-t accelerated non-gated free-breathing aortic 4D flow MRI measurements acquired in under 2 minutes (PEAK GRAPPA R=5; TRes=67.2ms; four k_y-k_z-space Cartesian fillings: linear, center-out, out-center-out, random; two spatial resolutions=3.5x2.3x2.6mm³, 4.5x2.3x2.6mm³), both in vitro and in 10 healthy volunteers. Despite lower image quality, the significantly shorter k-t accelerated datasets provided aortic hemodynamic indices in agreement with conventional respiratory-gated 4D flow measurements. Differences were non-significant when using linear and out-center-out k-space samplings (absolute differences≤22%). In conclusion, aortic 4D flow MRI in under 2 minutes is feasible with moderate underestimation of flow indices.

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