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Abstract #0510

Effective Connectivity Network of Emotion Regulation in Soldiers with Trauma

D Rangaprakash1,2, Michael N Dretsch3,4, Thomas A Daniel5,6, Thomas S Denney1,5,7, Jeffrey S Katz1,5,7, and Gopikrishna Deshpande1,5,7

1AU MRI Research Center, Department of Electrical and Computer Engineering, Auburn University, Auburn, AL, United States, 2Department of Psychiatry and Biobehavioral Sciences, University of California Los Angeles, Los Angeles, CA, United States, 3Human Dimension Division, HQ TRADOC, Fort Eustis, Fort Eustis, VA, United States, 4U.S. Army Aeromedical Research Laboratory, Fort Rucker, Fort Rucker, AL, United States, 5Department of Psychology, Auburn University, Auburn, AL, United States, 6Department of Psychology, Westfield State University, Westfield, MA, United States, 7Alabama Advanced Imaging Consortium, Auburn University and University of Alabama Birmingham, Birmingham, AL, United States

Conscious regulation of emotions is essential for sound functioning of an individual, while its disruption leads to several severe symptoms observed in psychiatric disorders like posttraumatic stress disorder (PTSD) and mild-traumatic brain injury (mTBI). While the brain regions activated in emotion regulation have been elucidated in prior works, an understanding of the underlying network has been elusive. Employing an emotion regulation task, we discovered the network of emotion regulation in healthy soldiers, and dysregulation in soldiers with comorbid PTSD/mTBI (N=59). Our work is significant given that we present, for the first time, the evidence for the network of emotion regulation/dysregulation.

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