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Abstract #0528

Clinical Evaluation of Whole-Heart Quantitative Adenosine Stress CMR with Motion-compensated L1-SPIRIT

Michael Salerno1, Yang Yang1, Stephen McHugh1, Eric Holland1, Jonathan Pan2, Craig H Meyer2, Angela Taylor1, and Christopher M Kramer3

1Department of Medicine, University of Virginia, Charlottesville, VA, United States, 2Department of Biomedical Engineering, University of Virginia, Charlottesville, VA, United States, 3Department of Radiology and Medical Imaging, University of Virginia, Charlottesville, VA, United States

Adenosine stress CMR has potential advantages over competing modalities for diagnosing coronary artery disease (CAD) including the ability to quantify myocardial perfusion, however current CMR techniques have limited spatial coverage. We perform a clinical assessment of the diagnostic performance of whole-heart spiral perfusion imaging using motion compensated compressed sensing for detection of CAD and demonstrate good image quality, minimal motion artifacts, and high diagnostic accuracy for both visual and quantitative evaluation.

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