Simultaneous multi-slice acceleration techniques excite, acquire, and reconstruct multiple slices simultaneously and provide the potential to create substantially accelerated clinical TSE protocols with similar spatial and contrast resolution to current TSE protocols. We quantified the signal-to-noise and contrast-to-noise ratios of various combinations of parallel and simultaneous multi-slice acceleration and compared two 4-fold accelerated TSE protocols against a clinical 2-fold accelerated TSE standard. Our results demonstrate that 4-fold TSE acceleration enables 43-60% shorter acquisition times with similar image quality, structural visibility and observer satisfaction than standard parallel imaging acceleration.
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