We first investigated the systemic outcome of a crowd underwent PSA-based screening and pre-biopsy mp-MRI, and demonstrated the predictive role of pre-biopsy mp-MRI for PCa by using an advanced machine learning-based approach. Here we answer one important question at the beginning of the paper: (1) mp-MRI coupled with PSA screening program can be used to detect PCa. By the constructed nomogram, the outcome of most patients could be accurately predicted in the first 1-yr follow-up period if they received a pre-biopsy mp-MRI examination, even without invasive TRUS biopsy.
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