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Abstract #1014

Effects of 5 alpha-Reductase Inhibitors on Detection of Prostate Cancer on MRI

Lori Mankowski Gettle1, Shivashankar Damodaran 2, David F. Jarrard2, and Frederick Kelcz1

1Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States, 2Urology, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States

5 alpha reductase inhibitors have shown promise in increasing the detection of prostate cancer in prior ultrasound studies. No studies have been performed looking at the effect of 5 alpha reductase inhibitors on increasing the conspicuity of prostate cancer in MRI. The purpose of this study was to determine if treatment with a 5 alpha reductace inhibitor could increase sensitivity for the detection of prostate cancer in the background setting of benign prostatic hypertrophy.

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