Abstract #1080

Functional and structural connectivity of the cingulate bundle related to future cognitive performance in MS

Katherine A Koenig¹, Erik Beall², Jian Lin¹, Ken Sakaie¹, Lael Stone³, Stephen Rao⁴, Micheal Phillips¹, and Mark Lowe¹

¹Imaging Institute, The Cleveland Clinic, Cleveland, OH, United States, ²HemaImaging, ³Neurological Institute, The Cleveland Clinic, Cleveland, OH, United States, ⁴Center for Brain Health, The Cleveland Clinic, Cleveland, OH, United States

This work assesses the relationship of resting state fMRI (rs-fMRI) and DTI of the posterior cingulum bundle to future cognitive performance. We find that rs-fMRI is related to performance on measures related to episodic memory, and radial diffusivity is related to performance on a measure of speed of processing.

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