Abstract #1096

Accelerated Diffusion-Sensitized MR Imaging of the Eye and Orbit at 3.0 T and 7.0 T free of Geometric Distortions Using a Combined RARE-EPI Acquisition Technique

Katharina Paul¹, Helmar Waiczies², André Kuehne², Till Huelnhagen¹, Eva Oberacker¹, Oliver Stachs³, and Thoralf Niendorf^1,2,4

¹Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrueck Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany, ²MRI.TOOLS GmbH, Berlin, Germany, ³Department of Ophthalmology, University of Rostock, Rostock, Germany, ⁴Experimental and Clinical Research Center (ECRC), a joint cooperation between the Charité Medical Faculty and the Max Delbrueck Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany

Diffusion-weighted imaging of the eye and orbit is an emerging MRI application to provide guidance during diagnostic assessment and treatment of ophthalmological diseases. RARE based diffusion-sensitized imaging (ms-RARE) provides images free of geometric distortions. Yet imaging speed, RF power deposition and artifacts by involuntary eye motion remain a concern. Combined acquisition techniques (CAT) merging RARE and EPI within one echo train offer the possibility to shorten acquisition times and relax specific absorption rate constraints. This study examines the applicability of RARE-EPI CAT for diffusion-sensitized imaging of the eye and orbit free of geometric distortions at 3.0 T and 7.0 T.

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