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Abstract #1194

Gaussian and non-Gaussian diffusion models for Differential Diagnosis of Prostate Cancer with in bore Transrectal MR-Guided Biopsy as a Pathological Reference

Chunmei Li1, Min Chen1, and Bing Wu2

1Beijing Hospital, Beijing, People's Republic of China, 2GE Healthcare, China

This study is to compare the utility of various metrics derived from different models based DWI and DKI in the differential diagnosis of prostate cancer. ADC, ADCslow, DDC, and MD values were significantly lower while MK value was significantly higher in prostate cancer lesions than those of prostatitis and BPH. Parameters derived from both Gaussian and non-Gaussian models could characterize prostate cancer. Diagnosis performance benefit was observed for DKI model as compared to MEM.

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