Abstract #1198

Echo-planar imaging with wave-CAIPI acquisition and reconstruction

Benedikt A Poser¹, Berkin Bilgic², Borjan A. Gagoski^3,4, Kâmil Uludağ¹, V Andrew Stenger⁵, Lawrence L Wald^2,6,7, and Kawin Setsompop^2,6

¹Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, Netherlands, ²Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, ³Department of Radiology, Harvard Medical School, Boston, MA, United States, ⁴Fetal-Neonatal Neuroimaging & Developmental Science Center, Boston Children’s Hospital, Boston, MA, United States, ⁵Department of Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI, United States, ⁶Harvard Medical School, Boston, MA, United States, ⁷Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, United States

wave-CAIPI allows for high undersampling factors and hence acquisition speed-up in anatomical imagines sequences including 3D GRE, 2D SMS-TSE and MP-RAGE (3D TFL). The coil array’s full 3D sensitivity encoding is exploited, resulting in negligible g-factor penalties even in highly accelerated scans. Echo-planar imaging (EPI) sequences, both 2D and 3D EPI with Cartesian blipped-CAIPI have recently brought tremendous speed-up to BOLD and diffusion imaging in the neurosciences. We here explore the potential of going beyond blipped-CAIPI EPI by incorporating sinusoidal z- and y- gradient wave perturbations into the EPI readout. Initial results are shown for 3D wave-CAIPI EPI at 7T.

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