Background Field Removal Technique using Non-regularized Variable Kernels Sophisticated Harmonic Artifact Reduction for Phase Data for Quantitative Susceptibility Mapping

QSM is relatively new biochemical and quantitative reconstruction method which directly estimates the iron distribution. It needs a precision of separation of local field from background field for measurement of accurate susceptibility value. We introduced a novel method using non-regularized variable kernels sophisticated harmonic artifact reduction for phase data (NR-VSHARP). The proposed method utilized multiple kernel sizes and minimization of norm only inside mask without any regularization parameter. NR-VSHARP enabled to estimate high accurate local field, compared with VSHARP. NR-VSHARP method provides high accurate local field map with saving cortical information.