Arterial spin labeling (ASL) is a non-contrast perfusion imaging method for MRI. However, 2D ASL suffers from low signal to noise ratio. 3D ASL is favorable to overcome the limitation of 2D ASL, but 3D acquisition is time-consuming, so acceleration of 3D ASL is highly desired. The new compressed sensing (CS) theory allows perfect reconstruction far below Nyquist rate. We implemented a novel 3D TSE acquisition using Cartesian Acquisition with SPiral Reordering (CASPR), which can be undersampled and combined with CS. Preliminary results show improved image quality using 3D Sparse-BLIP reconstruction that is comparable to fully sampled acquisition.
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