Abstract #1493

An algorithm for refocusing of T2* effects in bSSFP-MRF with relaxation corrections

Mingdong Fan¹, Danielle Kara¹, Jesse I. Hamilton², Nicole Seiberlich^2,3, Mark Griswold^2,3, and Robert Brown¹

¹Physics, Case Western Reserve University, Cleveland, OH, United States, ²Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States, ³Radiology, University Hospitals Case Medical Center, Cleveland, OH, United States

It is found that bSSFP-MRF is in general subject to T2* not T2 relaxation. Like traditional bSSFP, dephasing effects of intra-voxel inhomogeneities can be refocused in bSSFP-MRF with appropriate choices in TR, TE, and FA so that parameter maps are reflective of T2 rather than T2*. An algorithm is introduced and verified in simulation for refocusing intra-voxel dephasing at TE for bSSFP-MRF with corrections to previous work for relaxation effects previously assumed as negligible. These corrections are relevant for bSSFP-MRF in which T2 is not much larger than TR to ensure that T2 maps do not contain T2* effects.

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