Abstract #1540

Comparative T2 and T1ρ Mapping of Patellofemoral Cartilage under in situ Mechanical Loading with Prospective Motion Correction

Thomas Lange¹, Benjamin R. Knowles¹, Michael Herbst^1,2, Kaywan Izadpanah³, and Maxim Zaitsev¹

¹Department of Radiology, Medical Physics, Medical Center - University of Freiburg, Freiburg, Germany, ²John A. Burns School of Medicine, University of Hawaii, Honolulu, HI, United States, ³Department of Orthopedic and Trauma Surgery, Medical Center - University of Freiburg, Freiburg, Germany

Robust comparative T₂ and T_1ρ mapping of patellofemoral cartilage under in situ loading is demonstrated with prospective motion correction and T₂ and T_1ρ changes in response to loading are evaluated quantitatively, focusing on the load-bearing lateral patellar facet. T₂ and T_1ρ mapping were performed with equal spatial resolution and field of view for different loading conditions (0/20/40 kg). While no significant T₂ differences for the three loading conditions were observed, T_1ρ in superficial patellar cartilage was significantly reduced under loading. The quantitative findings suggest that T_1ρ is a more reliable and sensitive marker for load-induced changes than T₂.

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