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Abstract #1583

Analysis of T2 Relaxation Times in Vastus Lateralis Muscle after Anterior Cruciate Ligament Injury

Richard Dylan Lawless1, Peter A. Hardy2,3, Anders Andersen3,4, and Brian Noehren5

1College of Engineering, Department of Biomedical Engineering, Lexington, KY, United States, 2Department of Radiology, College of Medicine, Lexington, KY, United States, 3Magnetic Resonance Imaging and Spectroscopy Center, Lexington, KY, United States, 4Department of Neuroscience, College of Medicine, 5Department of Rehabilitation, College of Health Sciences, Lexington, KY, United States

Anterior cruciate ligament (ACL) injuries are associated with a persistent decrease in quadriceps muscle strength despite rehabilitation. Previous studies have shown that ACL injury results in muscle disorganization, which could account for the loss in strength. We sought to use dual-spin echo and multi-spin echo sequences to estimate T2 of the vastus lateralis in injured and uninjured limbs of twenty-two ACL injured subjects. T2 of the injured limb was significantly longer than the uninjured limb for both pulse sequences. Our results suggest that T2 relaxation may provide clinicians a means to quantitatively monitor muscle recovery after ACL injury.

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