Diagnosis of the ischemic lesion is challenging and often requires the use of pharmaco-mechanical methods. This study demonstrates the feasibility of using a susceptibility-based MRI technique with the multi-echo gradient and spin echo (MEGSE) sequence to assess the skeletal muscle oxygenation alternations in animal model of unilateral femoral artery embolization. The results shown that the skeletal muscle R2 decreases obviously from after femoral artery embolization, while R2’ increases correspondingly. MEGSE seems to be an appropriate method for the evaluation of skeletal muscle ischemia after embolization.
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