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Abstract #1664

Rapid cerebrovascular reactivity mapping: Comparison of a sinusoid protocol with the conventional block protocol

Nicholas P Blockley1, James W Harkin2, and Daniel P Bulte3

1FMRIB Centre, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom, 2Department of Physics, University of Oxford, Oxford, United Kingdom, 3Institute of Biomedical Engineering, University of Oxford, Oxford, United Kingdom

Cerebrovascular reactivity (CVR) mapping is a useful technique for stress testing the brain. However, clinical adoption of CVR mapping has so far been hindered by relatively long scan durations of 7-12mins. In this study we show that by using a sinusoidal carbon dioxide stimulus in place of a conventional block protocol, equivalent CVR maps can be produced in a much shorter scan duration of 3-5mins.

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