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Abstract #1783

Solving the free water elimination estimation problem by incorporating T2 relaxation properties

Quinten Collier1, Jelle Veraart1,2, Arnold J. den Dekker1,3, Floris Vanhevel4, Paul M. Parizel4, and Jan Sijbers1

1Vision Lab, University of Antwerp, Antwerp, Belgium, 2Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY, United States, 3Delft Center for Systems and Control, Delft University of Technology, Delft, Netherlands, 4Department of Radiology, Antwerp University Hospital, Antwerp, Belgium

The free water elimination (FWE) model fitting problem is inherently ill-conditioned, leading to the need for solutions that can avoid or deal with these kinds of fitting problems. In this work, we evaluate a model extension to the FWE model that exploits the T2-relaxation properties and subsequently leads to a well-posed fitting problem that can be easily solved using standard estimation techniques.

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