Ultra-high-field (7T) imaging already demonstrated to provide more robust DTI measurements in comparison to 1.5 and 3T in the brain but, to the best of our knowledge, it was not applied for DTI measurements on human muscles. Our results showed higher SNR as well as an overall improvement in DTI metrics for the entire calf muscle at 7T than at 3T. Single muscle analyses (gastrocnemii, tibialis anterior) demonstrated more heterogeneous results. Future studies including a larger population and considering technical challenges (e.g.,RF inhomogeneity, gradient performance) are necessary to assess if 7T may provide higher benefits in specific muscles.
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